Regenerative microneedling. SkinPen with exosomes, PRP, PRF, GHK-Cu, PDRN.

The base treatment is straightforward. A SkinPen Precision device — twelve sterile, single-use micro-needles — passes across the skin at a controlled depth (typically 0.5 to 2.0 mm depending on the area). Each pass creates thousands of channels that the body responds to by initiating a wound-healing cascade. Collagen and elastin are remodeled over the following weeks. Skin texture, fine lines, and superficial scarring improve.

On its own, microneedling is a reliable, low-risk workhorse. For patients who only want texture refinement, basic microneedling — without add-ons — is often the right answer. Our sister studio Ruth Swissa offers that at ruthswissa.com/services/skin-services/microneedling/.

What changes the math is the open channel. For roughly an hour after needling, the skin is unusually permeable. A topical applied during or immediately after that window reaches the dermis — not just the stratum corneum. That's the regenerative half: we're not relying on the topical's molecular size to push through intact barrier; we're letting needling do the carrying.

Three sessions, four weeks apart, is the standard initial series. Some patients with significant scarring or photoaging benefit from a fourth session at the eight-week mark from session three. We discuss this honestly at session two — if the response is strong, three is enough; if the indication is heavy, we plan for four.

Visible change starts at two weeks and matures over twelve. The first session produces the clearest before-and-after only in retrospect — patients tend to underestimate change because they see their face daily. By session three, most patients can see it in their own mirror.

After the initial series, maintenance is one or two sessions per year. Patients who're treating active concerns (post-acne scarring, melasma) may stay on a closer cadence until the indication stabilizes.

Regenerative microneedling in Los Angeles typically ranges from $600 to $1,500 per session, depending on the add-on. PRP sessions sit at the lower end, $600 to $1,500. Exosome sessions, EZ Gel, and under-eye PRF cluster at the upper end, $1,200 to $1,500. Most plans run three to four sessions over four to six months, with package pricing typically discounting the per-session rate.

Add-on category is the dominant cost driver. PRP and PRF are drawn from your blood and processed in-house — materials cost is largely the chair time. Exosomes are externally sourced from a manufacturer, cold-shipped, stored carefully, and priced accordingly. PDRN sits between the two, with growing clinical interest and a price point above PRP but below exosomes. GHK-Cu is the most accessible peptide adjunct.

Treatment area matters next. Full-face sessions sit at the top of the per-session range. Face plus neck and décolleté costs more because the pass is longer and the product volume larger. Targeted single-area work — focal scarring, a single under-eye treatment — runs lower per session but typically needs more visits to produce the same cumulative result.

Injector and clinic protocol set the upper bound. Practices with on-site PRP processing, multiple add-on options stocked, and a clinician who selects based on indication rather than upsell will price toward the top of the range. The premium reflects expertise and inventory, both of which matter for outcomes.

Location within LA is the final variable. Beverly Hills addresses sit at the top of the regenerative-microneedling market. Calabasas and the Valley generally below for comparable expertise. The spread reflects real-estate cost more than clinical capability.

RF microneedling adds radiofrequency energy to the needling pass. Face sessions in LA typically run $700 to $900; neck $500 to $800. RF targets skin laxity and deeper texture in a way pure needling can't. Regenerative microneedling targets skin quality and collagen rebuilding without the energy component. Both have a place; the choice depends on whether laxity or quality is the dominant concern.

Fractional CO₂ resurfacing is the more aggressive adjacent option — $600 to $800 per face session, with one to two weeks of social downtime. CO₂ resurfaces the top layers of skin. Regenerative microneedling rebuilds underneath without ablating the surface. Patients chasing a fast, dramatic surface change lean CO₂; patients chasing structural improvement without downtime lean regenerative.

The Vampire Facial — PRP microneedling under its branded name — is the same procedure described differently. Pricing in LA aligns with PRP regenerative pricing: $600 to $1,500 per session. The marketing name shouldn't add to the price; if it does, the practice is charging for the brand rather than the work.

For patients deciding between protocols, the honest framing is: each addresses a different layer of the same problem. Many patients end up running RF microneedling and regenerative microneedling on alternating cycles across a year, with CO₂ as a periodic intervention. The cost adds up when the protocols aren't planned together; coordinated planning usually saves money across a multi-year arc.

Pricing at Swissa Med Spa is determined at consultation, where we match the add-on to your skin and goals. A written plan with line-item per-session and package totals is shared before any treatment is booked. The plan is the product; the session is the unit.